Responsible Research and Innovation (RRI) is a very topical concept at European Union level, and an inspirational one for science centres and museums. This session highlights how RRI tools can be used to create development processes that put users at the centre of attention. The implementation of RRI policies in European research programmes means a new era, where we focus not only on “what”; but also on “how” we develop responsibly. It requires inclusion, diversity, openness, transparency, anticipation and responsiveness. Dialogue and participatory actions should be embedded in projects from the very beginning. In turn this will give us engaged and enlightened audiences, and will support science centres and museums as important players of the science and society agenda.