Science et Cité specialises in low-threshold and innovative forms of communication, often with direct contact between researchers and the population. In doing so, the Foundation promotes the appreciation and understanding of all sciences and addresses their opportunities and limitations. Similarly, the foundation also encourages civil society to provide feedback to the sciences, especially on questions of values.

Science et Cité focuses on topics that are of current interest and concern to society, and uses them to promote knowledge and the formation of opinions for the benefit of democracy. Sustainability issues are of particular importance in this context.

In all three language regions, Science et Cité employees manage projects that are aimed at children and teenages as well as adults. Projects, both analogue and digital, focus on a specific target audience. To achieve this, the Foundation works with a wide range of partners and stakeholders involved in education, science, business, culture and politics.